Cialis drug is different from other erectile dysfunction drugs. Doctor Maria Hernandez , who worked on Cialis for a decade now says that structurally this ED drug is different from other brands. Here, the duration period is long of 36 hours. So, anyone using Generic Cialis 60 mg pills (high dose) for erection issue should take its long period of impact in mind. Dr Maria feels that if a male has to move immediately after sex, he should not use Cialis. But it is the best drug for weekend to get the erection ability for a long period. It eliminates the need for another dose of ED drug on weekends.